In order for an embryo to implant into the lining of the womb and a pregnancy occur, whether it is after IVF or after natural conception, it is necessary for the embryo to push out from or ‘hatch’ out of its outer coating called the “zona pellucida”.

Some studies suggest that older women with no obvious reasons for repeated IVF failure possibly have a problem with the zona pellucida. This may mean that the embryo fails to hatch and is therefore unable to implant. It is possible that a technique called Assisted Hatching, where a very small hole is made in the zona pellucida may help in these cases.

Assisted Hatching is a technique which involves using a very fine needle and an acid solution to make a hole in the zona pellucida. Because an acid solution is used, there is a very small chance that some may come into contact with the embryo and damage the cells inside.

If Assisted Hatching has been recommended by the Consultant, it is essential that you inform the reception when you book your treatment cycle. One of the Senior Embryologists will confirm the procedure on the day of egg collection with you, and arrange the details of your transfer day.
Important: At present there are no definitive studies to determine whether there is real value in this procedure, and we therefore cannot give any realistic data as to success.

It is not recommended to use this technique on embryos that are to be frozen or with embryos developing to the blastocyst stage.

If you wish to discuss the procedure in more detail please telephone the embryology office on 020 8383 8108.